The St. Louis Cardinals (77-77) will lean on Brendan Donovan when they host Jose Ramirez and the Cleveland Guardians (90-65) at Busch Stadium on Saturday, Sept. 21. The first pitch will be thrown at 7:15 p.m. ET.

Sportsbooks have listed the Cardinals (-115) as moneyline favorites versus the Guardians (-105). Bookmakers have set the over/under for this matchup at 8 runs.

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Cardinals vs. Guardians Game Info

• Date: Saturday, September 21, 2024
• Time: 7:15 p.m. ET
• Location: St. Louis, Missouri
• Venue: Busch Stadium
• TV Channel: BSGL
• Live Stream: Watch this game on Fubo

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Matchup Betting Info

• Moneyline Favorite: Cardinals -115
• Moneyline Underdog: Guardians -105
• Over/Under: 8 runs (Over: -115, Under: -105)

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Cardinals Probable Starting Pitcher

• Miles Mikolas (8-11 with a 5.49 ERA and 114 strikeouts in 160 2/3 innings pitched) makes the start for the Cardinals, his 31st of the season.
• In his most recent time out on Sunday, the righty went five innings against the Toronto Blue Jays, giving up two earned runs while surrendering three hits.
• Mikolas heads into this game with 14 quality starts under his belt this year.
• Mikolas is trying to collect his 22nd start of five or more innings this year in this matchup.
• In three of his appearances this season he did not allow an earned run.

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Cardinals Hitting & Pitching Performance

• The Cardinals rank 23rd in MLB play with 156 home runs. They average one per game.
• St. Louis’ .388 slugging percentage is 21st in baseball.
• The Cardinals’ .246 batting average ranks 13th in the majors.
• St. Louis is the 25th-highest scoring team in MLB play, averaging 4.1 runs per game (627 total).
• The Cardinals’ .309 on-base percentage ranks 15th in MLB.
• Cardinals batters strike out 8.1 times per game, the ninth-fewest strikeouts in the majors.
• St. Louis’ 4.07 team ERA ranks 16th among all MLB pitching staffs.
• The pitching staff for St. Louis has a collective 8.2 K/9, the fifth-worst in the majors.
• The Cardinals have the 17th-ranked WHIP in the majors (1.263).

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